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다음 판		이전 판
med:hcg [2023/04/25 06:29] – V_Lmed:hcg [2025/01/21 00:48] (현재) – [농도] V_L
줄 2: 줄 2:
 ======사람융모막홀몬 (human chorionic gonadotropin; hCG)====== ======사람융모막홀몬 (human chorionic gonadotropin; hCG)======
  
-태반(placenta)에서 분비되는 홀몬으로 임신 극초반에는 Cytotrophoblast에서도 분비되지만, 그 이후는 syncytiotrophoblast에서 분비된다.  +태반(placenta)에서 분비되는 홀몬으로 임신 극초반에는 Cytotrophoblast에서도 분비되지만, 그 이후는 syncytiotrophoblast에서 분비된다.
- +
  
 =====농도===== =====농도=====
    
-  * ** 5mIU/ml**이하는 비임신. +  * ** 5 mIU/ml**이하는 비임신. 
-  * **25mIU/ml**이상은 임신. +  * **25 mIU/ml**이상은 임신. 
   * 5~25는 잘모름.   * 5~25는 잘모름.
  
줄 16: 줄 14:
   * 신속(얼리체크) 에서는 10 정도부터도 두줄로 나온다.   * 신속(얼리체크) 에서는 10 정도부터도 두줄로 나온다.
  
 +수치 48이면 약 9-10일 정도 있어야 아기집 보임. (48 → 96 → 192 → 384 → 768 → 1536)
  
 {{:med:hcg_levels_over_time.jpg|}} {{:med:hcg_levels_over_time.jpg|}}
- 
  
   * At 14 DPO, the average HCG level is 48 mIU/ml, 17-119 mIU/ml.    * At 14 DPO, the average HCG level is 48 mIU/ml, 17-119 mIU/ml. 
줄 30: 줄 28:
   * At 22 DPO, the average HCG level is 1287 mIU/ml,  185-3279 mIU/ml.    * At 22 DPO, the average HCG level is 1287 mIU/ml,  185-3279 mIU/ml. 
   * At 23 DPO, the average HCG level is 2034 mIU/ml,  506-4660 mIU/ml.    * At 23 DPO, the average HCG level is 2034 mIU/ml,  506-4660 mIU/ml. 
-  * At 24 DPO, the average HCG level is 2637 mIU/ml, 540-10,000 mIU/ml. +  * At 24 DPO, the average HCG level is 2637 mIU/ml, 540-10,000 mIU/ml.
  
 DPO : Days past ovulation 배란 후 날수 DPO : Days past ovulation 배란 후 날수
- 
  
 {{:med:beta_hcg_in_pregnancy.jpg|}} {{:med:beta_hcg_in_pregnancy.jpg|}}
줄 43: 줄 40:
   * 2-3 months:10,000-100,000 mIU/ml    * 2-3 months:10,000-100,000 mIU/ml 
   * 2nd trimester: 3,000-50,000 mIU/ml    * 2nd trimester: 3,000-50,000 mIU/ml 
-  * 3rd trimester: 1,000-50,000 mIU/ml  +  * 3rd trimester: 1,000-50,000 mIU/ml
- +
  
   * Non-pregnant females: <5.0 mIU/ml    * Non-pregnant females: <5.0 mIU/ml 
-  * Postmenopausal females: <9.5 mIU/ml +  * Postmenopausal females: <9.5 mIU/ml
  
 =====기타===== =====기타=====
   * 10주에 최고치, 20주가 되면 바닥으로 떨어진다. (( The level will reach its peak in the first **8 - 11** weeks of pregnancy and then will decline))   * 10주에 최고치, 20주가 되면 바닥으로 떨어진다. (( The level will reach its peak in the first **8 - 11** weeks of pregnancy and then will decline))
-  * 정상적인 임신이라면 hCG ** 1,000 – 2,000 mIU/mL** 에서 자궁내에 [[med:fetal_biometry#gestational sac|임신낭(G-sac)]]이 보인다.  +  * 정상적인 임신이라면 hCG ** 1,000 – 2,000 mIU/mL** 에서 자궁내에 [[med:fetal_biometry#gestational sac|임신낭(G-sac)]]이 보인다.
  
 [[med:h_mole|]] 환자가 이후에 다시 [[med:h_mole|]]될 확률은 1.8%에 불과히다. [[med:h_mole|]] 환자가 이후에 다시 [[med:h_mole|]]될 확률은 1.8%에 불과히다.
줄 59: 줄 53:
   * For HCG levels <1200 mIU/ml, the expected doubling time is 48-72 hours.    * For HCG levels <1200 mIU/ml, the expected doubling time is 48-72 hours. 
   * For HCG levels 1200 to 6000 mIU/ml, the expected doubling time is 72-96 hours.    * For HCG levels 1200 to 6000 mIU/ml, the expected doubling time is 72-96 hours. 
-  * For HCG levels >6000 mIU/ml, the expected doubling time is >96 hours. +  * For HCG levels >6000 mIU/ml, the expected doubling time is >96 hours.
  
  /* According to the American Pregnancy Association, the two- to three-day guideline holds true in 85% of normal pregnancies. So that means about 15% of viable pregnancies may have slower hCG doubling times. In one 2004 study, researchers found that hCG could increase as little as 53% over a period of two days even in a normal pregnancy, although slow rising hCG levels are less common in normal pregnancies. (Keep in mind that the 53% increase was the slowest rise ever recorded for hCG levels in early pregnancy and that slow-rising hCG levels do mean complications in many cases.) */  /* According to the American Pregnancy Association, the two- to three-day guideline holds true in 85% of normal pregnancies. So that means about 15% of viable pregnancies may have slower hCG doubling times. In one 2004 study, researchers found that hCG could increase as little as 53% over a period of two days even in a normal pregnancy, although slow rising hCG levels are less common in normal pregnancies. (Keep in mind that the 53% increase was the slowest rise ever recorded for hCG levels in early pregnancy and that slow-rising hCG levels do mean complications in many cases.) */
- 
  
 =====반감기===== =====반감기=====