오픈위키

사람융모막홀몬 (human chorionic gonadotropin; hCG)

태반(placenta)에서 분비되는 홀몬으로 임신 극초반에는 Cytotrophoblast에서도 분비되지만, 그 이후는 syncytiotrophoblast에서 분비된다.

농도

  • 5mIU/ml이하는 비임신.
  • 25mIU/ml이상은 임신.
  • 5~25는 잘모름.

  • At 14 DPO, the average HCG level is 48 mIU/ml, 17-119 mIU/ml.
  • At 15 DPO, the average HCG level is 59 mIU/ml, 17-147 mIU/ml.
  • At 16 DPO, the average HCG level is 95 mIU/ml, 33-223 mIU/ml.
  • At 17 DPO, the average HCG level is 132 mIU/ml, 17-429 mIU/ml.
  • At 18 DPO, the average HCG level is 292 mIU/ml, 70-758 mIU/ml.
  • At 19 DPO, the average HCG level is 303 mIU/ml, 111-514 mIU/ml.
  • At 20 DPO, the average HCG level is 522 mIU/ml, 135-1690 mIU/ml.
  • At 21 DPO, the average HCG level is 1061 mIU/ml, 324-4130 mIU/ml.
  • At 22 DPO, the average HCG level is 1287 mIU/ml, 185-3279 mIU/ml.
  • At 23 DPO, the average HCG level is 2034 mIU/ml, 506-4660 mIU/ml.
  • At 24 DPO, the average HCG level is 2637 mIU/ml, 540-10,000 mIU/ml.

DPO : Days past ovulation 배란 후 날수

  • 0-1 week: 0-50 mIU/ml
  • 1-2 weeks: 40-300 mIU/ml
  • 3-4 weeks: 500-6,000 mIU/ml
  • 1-2 months:5,000-200,000 mIU/ml
  • 2-3 months:10,000-100,000 mIU/ml
  • 2nd trimester: 3,000-50,000 mIU/ml
  • 3rd trimester: 1,000-50,000 mIU/ml
  • Non-pregnant females: <5.0 mIU/ml
  • Postmenopausal females: <9.5 mIU/ml
  • 10주에 최고치, 20주가 되면 바닥으로 떨어진다. 1)
  • 정상적인 임신이라면 hCG 1000IU에서 자궁내에 임신낭(G-sac)이 보인다.

mole 환자가 이후에 다시 mole 될 확률은 1.8%에 불과히다. 따라서 거의 위험성은 없다.

  • For HCG levels <1200 mIU/ml, the expected doubling time is 48-72 hours.
  • For HCG levels 1200 to 6000 mIU/ml, the expected doubling time is 72-96 hours.
  • For HCG levels >6000 mIU/ml, the expected doubling time is >96 hours.

According to the American Pregnancy Association, the two- to three-day guideline holds true in 85% of normal pregnancies. So that means about 15% of viable pregnancies may have slower hCG doubling times. In one 2004 study, researchers found that hCG could increase as little as 53% over a period of two days even in a normal pregnancy, although slow rising hCG levels are less common in normal pregnancies. (Keep in mind that the 53% increase was the slowest rise ever recorded for hCG levels in early pregnancy and that slow-rising hCG levels do mean complications in many cases.)

낙태 후 임신홀몬검사는 최소 2~3주 후에 시행해야 정확히 판정할 수 있다.

1)
The level will reach its peak in the first 8 - 11 weeks of pregnancy and then will decline

연결문서

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2.8 KB med/hcg.txt · 마지막으로 수정됨 2017/07/20 08:37 저자 V_L V_L

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