문서의 이전 판입니다!


ASCUS

  1. 80-90%에서 없어지기 때문에 3-6개월 후 재검으로 충분.
  2. 경과관찰이 어렵거나, 기타 상황에 따라 경부확대경 & 조직검사
  3. HPV test

Abnormal cervical cytology in pregnancy

자궁경부의 상처는 조기진통 및 조산으로 이어질 수 있어, 산모의 처치는 다름.

PAP
ASC-US 분만 후 재검
ASC-H, LSIL, HSIL 확대경 ± 조직검사
Punch Biopsy
CIN I 분만 후 재검
CIN II,III3-4개월 간격 확대경 & PAP 혹은 분만 후 재검

ASC-US

ASC-US + HPV(+) → 콜포스코피(±Bx) 혹은 분만 후 재검

Pregnant women with ASC-US + and a positive HPV test may elect to have colposcopy during pregnancy or wait until at least six weeks after delivering their baby.

The reason for this recommendation is that cervix appears somewhat different during pregnancy, which can make it difficult to determine if an area appears abnormal due to pregnancy or due to precancerous changes. In addition, most mild abnormalities resolve over time without treatment.

ASCCP 2006 consensus guideline

  • ASC-US : CIN 2 이상(15%), cervical cancer (0.2%) 이 data는 HPV 중 위험type이 positive였던 사람들의 data임
  • ASC-H : CIN2 이상 (38%) , cervical cancer (2.7%)

ASC-H

Pregnant women with ASC-H should have a colposcopy. This is because ASC-H is more likely than ASC-US to be caused by a precancerous change. Management after colposcopy depends upon the result of the biopsy (see below).

LSIL

Colposcopy is recommended for pregnant women with LSIL, similar to non-pregnant women. Management after colposcopy depends upon what the biopsy shows.

Management after colposcopy

  • CIN 1 — Pregnant women with CIN 1 are usually advised to defer further evaluation and treatment until at least 6 weeks after delivery of the baby. The reason for this recommendation is that most mild abnormalities will resolve over time without treatment.
  • CIN 2 or 3 — If there is evidence of CIN 2 or 3, colposcopy and cervical cytology testing may be done every 3 to 4 months during the pregnancy, or further evaluation may be deferred until at least 6 weeks after the woman delivers her baby. Treatment to remove the abnormal area is not recommended during pregnancy.

The reason for this recommendation is that CIN 2 or 3 is caused by precancerous changes that have the potential to become cancerous when untreated. This is a slow process that takes many months to years. As long as the abnormality is monitored, it is not necessary to remove the area (and increase the risk of preterm delivery or miscarriage) until after delivery.

연결문서