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med:keloid [2016/08/23 16:22] – V_Lmed:keloid [2016/08/23 16:27] (현재) – [병변내 스테로이드 주사] V_L
줄 30: 줄 30:
 ====병변내 스테로이드 주사==== ====병변내 스테로이드 주사====
  
 +효능 보고는 50~100%까지 다양함. 
  
 +Intralesional triamcinolone injections are commonly used after surgery in combination with surgical excision of the pathological scar and decrease the recurrence rates by an average of 50%. The rates of response to intralesional corticosteroid injections vary from 50% to 100%. Triamcinolone injection alone also is effective in reducing the volume of lesions in the majority of patients [16,17,18,19]. Previous literature has reported that mean scar volumes are reduced from 0.73±0.701 mL at baseline to 0.14±0.302 mL after monthly intralesional injections of triamcinolone acetonide [20,21].
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 + the pain of the injections, thinning and atrophy of the skin and subcutaneous tissues, the development of steroid acne, capillary dilation, the development of secondary lymphogenous and linear hypopigmentation 
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 + The injection should be intradermal, not subcutaneous, to avoid causing a dent in the skin.
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 + Typical intramuscular doses are 0.5–1 mg/kg body weight (40-80 mg for typical adult), which may be repeated every 30 days for 3 to 6 months.
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 + The initial dose per injection site will vary depending on the lesion being treated. Generally, 0.1–0.2 mL is injected per square centimetre of involved skin. The total dose should not normally exceed 1 or 2 mL per dose. It can be repeated every 4 to 8 weeks.
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 + 1회 0.2~1mg 씩 10mg 까지 주 1회 주사.
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 + 
 treat a dermal inflammatory process directly. treat a dermal inflammatory process directly.