Endometrium

자궁내막은 임신과 월경을 담당하는 기관으로 월경주기에 따라 변화한다.

최대의 두께는 보통 5~7 mm 정도이다.

자궁내막의 주기는 크게 배란 전후로 나누어 증식기(proliferative phase)와 분비기(secretory phase)로 대별하기도 하고, 다시 세분하여 다음과 같이 5 분기로 나누기도 한다

  • 월경후기(postmenstrual phase)
  • 증식기(proliferative phase)
  • 분비기(secretory phase)
  • 월경전기(premenstrual phase)
  • 월경기(menstrual phase)

자궁내막 증식증 (Endometrial Hyperplasia)

Endometrial carcinoma

Pretreatment evaluation

  • Routine examination
  • D & C
  • Chest radiography
  • Cystocopy, colonoscopy, intravenous pyelography, barium enema, Abdominal/pelvis CT: Optional
  • MRI: to assess myometrial invasion

*Serum CA-125

Staging

Stage IA: tumor is limited to the endometrium Stage IB: invasion of less than half the myometrium Stage IC: invasion of more than half the myometrium Stage IIA: endocervical glandular involvement only Stage IIB: cervical stromal invasion Stage IIIA: tumor invades serosa or adnexa, or malignant peritoneal cytology Stage IIIB: vaginal metastasis Stage IIIC: metastasis to pelvic or para-aortic lymph nodes Stage IVA: invasion of the bladder or bowel Stage IVB: distant metastasis, including intraabdominal or inguinal lymph nodes

Treatment

Intermediate to High risk: Chemotherapy Platinum+ Doxorubicin or Paclitaxel + Platinum

역링크