Infection

MRSA

Community-Acquired MRSA Soft Tissue Infections The study also suggests that prescription of ceftriaxone facilitates discharge of patients with cellulitis because they can return once daily for medication. Cefazolin, the study found, does not similarly allow patients to be discharged, since it must be taken 2 or 3 times daily and since patients had difficulty in learning how to self-administer it.

Once the clinician excludes the above-mentioned soft tissue infections and settles on a diagnosis of cellulitis, then the main pathogens to consider are Staphylococcus aureus and a variety of hemolytic streptococci. While cefazolin and ceftriaxone have been useful treatments for the garden variety of cellulitis in the past, in 2004 we find ourselves in a changing era of antibiotic resistance, particularly with regard to S aureus. Hospital-associated methicillin-resistant S aureus (MRSA) has progressed dramatically since the 1960s, and the prevalence of MRSA is 50% or greater in many US hospitals.

Most cellulitis is community-acquired, yet even here we are experiencing a virtual explosion of MRSA soft tissue infections in most parts of the country. Community-acquired MRSA infections of the soft tissues include impetigo, furunculosis, folliculitis, scalded skin syndrome, cellulitis, and necrotizing fasciitis. Physicians need to be aware that methicillin; nafcillin; oxacillin; and all cephalosporins, including ceftriaxone and cefazolin, are ineffective in the treatment of these MRSA infections.

Both CA-MRSA and HA-MRSA are resistant to traditional anti-staphylococcal beta-lactam antibiotics, such as cephalexin. CA-MRSA has a greater spectrum of antimicrobial susceptibility, including to sulfa drugs (like co-trimoxazole/trimethoprim-sulfamethoxazole), tetracyclines (like doxycycline and minocycline) and clindamycin, but the drug of choice for treating CA-MRSA has not been established.[15]. HA-MRSA is resistant even to these antibiotics and often is susceptible only to vancomycin.

Gram stain

Gram negative diplococci N. gonorrhoeae (the "gonococcus")
Gram negative bacilli Escherichia coli
Gram-positive cocci Staphylococcus, Streptococcus
Gram-positive Bacilli Lactobacillus

condyloma Accuminata Management Guidelines

http://www.medicine.org.hk/hksdv/journal/200103-10.pdf

Trichloroacetic acid (TCA)80-90% solution can. be used to treat genitalwarts

Trichloroacetic Acid 95%

(Methylchloroform) 트리클로로아세트산 CH3CCl3 EP 500g,1Kg,25Kg

http://www.kcichem.com/reagent/reagent_t.htv

Metronidazole

부작용

질염 등 감염증에 사용하는 메트로니다졸(metronidazole)이란 항생제와 술을 함께 먹으면 디설피란 반응(disulfiram reaction)이 나타날 수 있다. 구토, 구역을 포함해 혈압, 호흡기능에 중대한 부작용을 유발한다. 경구제, 주사제 1) 심혈관계: 홍조, T wave flat 2) 중추신경계: 운동실조, 혼란, 졸음, 열, 두통, 불면증, 발작, 현기증 3) 피부: 홍반성발진, 두드러기 4) 내분비 및 대사계: 디설피람 유사 증상, 리비도 감소, 월경곤란증 5) 위장관계: 오심(12% 이상), 식욕부진, 변비, 설사, 설염, 직장염, 위염, 구토, 구강건조증 6) 비뇨기계: 방광염, 어두운 소변, 배뇨곤란, 다뇨, 질염, 뇨실금 7) 조혈기계: 호중구 감소증, 혈소판 감소증 8) 근골격근계: 말초신경병증 9) 호흡기계: 인후염, 비염, 코막힘 10) 기타: 감기유사 증상, 모닐리아증

유로박솜 UROVAXOM

유로박솜을 복용하면 E.coli 에 대한 특이적 항체가 분비돼 선천적 면역에 관여하는 면역인자가 활성화된다. 결국 E.coli 뿐 아니라 다른 원인균에 의한 요로감염도 감소시키는 결과를 가져오는 것이다.